STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murDuDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (446 aa)    
Predicted Functional Partners:
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
 
 0.998
CDE28706.1
Putative UDP-N-acetylmuramate--L-alanine ligase; Product inferred by homology to UniProt.
 
0.995
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 0.994
murB
uDP-N-acetylenolpyruvoylglucosamine reductase 1; Cell wall formation.
  
 0.991
murF
uDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.989
CDE28182.1
uDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase; Product inferred by homology to UniProt; Belongs to the MurCDEF family. MurE subfamily.
 
 0.985
murE
uDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
0.975
CDE28320.1
pOTRA domain protein FtsQ-type; Essential cell division protein.
  
  
 0.972
murB-2
uDP-N-acetylenolpyruvoylglucosamine reductase 2; Cell wall formation.
  
 0.964
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
  
 0.959
Your Current Organism:
Catenibacterium sp. CAG290
NCBI taxonomy Id: 1262767
Other names: C. sp. CAG:290, Catenibacterium sp. CAG:290
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.