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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC07194.1iMP dehydrogenase; Product inferred by homology to UniProt. (501 aa)    
Predicted Functional Partners:
guaA
gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
 0.998
CDC07276.1
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.935
CDC05989.1
Nucleoside-triphosphatase; Product inferred by homology to UniProt.
  
 0.933
CDC05870.1
cBS protein; Product inferred by homology to UniProt.
    
 0.920
CDC05730.1
Hypoxanthine phosphoribosyltransferase; Product inferred by homology to UniProt; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.911
CDC06278.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
 0.909
CDC06466.1
Predicted hydrolase (HAD superfamily); Product inferred by homology to UniProt.
  
 0.909
pyrG
cTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 0.908
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
  0.884
CDC07147.1
Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Product inferred by homology to UniProt; Belongs to the TtcA family.
  
 
  0.884
Your Current Organism:
Clostridium sp. CAG343
NCBI taxonomy Id: 1262796
Other names: C. sp. CAG:343, Clostridium sp. CAG:343
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