node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC77568.1 | CDC77852.1 | BN818_00089 | BN818_00178 | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | Thymidylate kinase; Product inferred by homology to UniProt. | 0.690 |
CDC77568.1 | CDC79022.1 | BN818_00089 | BN818_00550 | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.470 |
CDC77568.1 | CDC81774.1 | BN818_00089 | BN818_01456 | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | dCMP deaminase; Product inferred by homology to UniProt. | 0.548 |
CDC77568.1 | dut | BN818_00089 | BN818_01323 | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.645 |
CDC77568.1 | thyX | BN818_00089 | BN818_00179 | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.663 |
CDC77852.1 | CDC77568.1 | BN818_00178 | BN818_00089 | Thymidylate kinase; Product inferred by homology to UniProt. | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | 0.690 |
CDC77852.1 | CDC79022.1 | BN818_00178 | BN818_00550 | Thymidylate kinase; Product inferred by homology to UniProt. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.518 |
CDC77852.1 | CDC81774.1 | BN818_00178 | BN818_01456 | Thymidylate kinase; Product inferred by homology to UniProt. | dCMP deaminase; Product inferred by homology to UniProt. | 0.909 |
CDC77852.1 | CDC82034.1 | BN818_00178 | BN818_01524 | Thymidylate kinase; Product inferred by homology to UniProt. | 5'-nucleotidase YfbR; Product inferred by homology to UniProt. | 0.861 |
CDC77852.1 | adk | BN818_00178 | BN818_00985 | Thymidylate kinase; Product inferred by homology to UniProt. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.700 |
CDC77852.1 | dut | BN818_00178 | BN818_01323 | Thymidylate kinase; Product inferred by homology to UniProt. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.930 |
CDC77852.1 | thyX | BN818_00178 | BN818_00179 | Thymidylate kinase; Product inferred by homology to UniProt. | Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.979 |
CDC78203.1 | dut | BN818_00290 | BN818_01323 | dNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.819 |
CDC79022.1 | CDC77568.1 | BN818_00550 | BN818_00089 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | c_GCAxxG_C_C family protein; Product inferred by homology to UniProt. | 0.470 |
CDC79022.1 | CDC77852.1 | BN818_00550 | BN818_00178 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Thymidylate kinase; Product inferred by homology to UniProt. | 0.518 |
CDC79022.1 | CDC81774.1 | BN818_00550 | BN818_01456 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dCMP deaminase; Product inferred by homology to UniProt. | 0.423 |
CDC79022.1 | dut | BN818_00550 | BN818_01323 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.932 |
CDC79118.1 | adk | BN818_00592 | BN818_00985 | Anaerobic ribonucleoside-triphosphate reductase; Product inferred by homology to UniProt. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.551 |
CDC79118.1 | dut | BN818_00592 | BN818_01323 | Anaerobic ribonucleoside-triphosphate reductase; Product inferred by homology to UniProt. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.947 |
CDC81038.1 | adk | BN818_01206 | BN818_00985 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.498 |