STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC03013.1Methylenetetrahydrofolate reductase; Product inferred by homology to UniProt. (593 aa)    
Predicted Functional Partners:
CDC03183.1
Homocysteine S-methyltransferase; Product inferred by homology to UniProt.
 
 
0.999
CDC01848.1
Cystathionine gamma-synthase; Product inferred by homology to UniProt.
  
 0.998
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 0.997
CDC02315.1
Methionine synthase II (Cobalamin-independent); Product inferred by homology to UniProt.
  
 0.997
CDC03184.1
Vitamin B12 dependent methionine synthase activation domain; Product inferred by homology to UniProt.
 
 
 0.994
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.984
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.976
CDC02595.1
Homoserine dehydrogenase; Product inferred by homology to UniProt.
  
 
 0.974
CDC02596.1
Aspartokinase; Product inferred by homology to UniProt; Belongs to the aspartokinase family.
  
 
 0.973
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.960
Your Current Organism:
Eubacterium sp. CAG202
NCBI taxonomy Id: 1262884
Other names: E. sp. CAG:202, Eubacterium sp. CAG:202
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