STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCZ12891.1Putative uncharacterized protein; Product inferred by homology to UniProt. (410 aa)    
Predicted Functional Partners:
gyrA
dNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.799
ribBA
3 4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.604
CCZ12260.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
   
   0.516
CCZ12781.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
    
 0.502
CCZ12889.1
Thioredoxin; Product inferred by homology to UniProt.
   
   0.479
CCZ12892.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
       0.432
CCZ12893.1
Group 2 glycosyl transferase; Product inferred by homology to UniProt.
       0.432
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
    0.410
Your Current Organism:
Prevotella sp. CAG1092
NCBI taxonomy Id: 1262919
Other names: P. sp. CAG:1092, Prevotella sp. CAG:1092
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