STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXdNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (517 aa)    
Predicted Functional Partners:
CCZ82981.1
dNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.994
CCZ83594.1
dNA polymerase III catalytic subunit DnaE type; Product inferred by homology to UniProt.
 
 0.989
CCZ83370.1
dNA polymerase III alpha subunit (Gram-positive type); Product inferred by homology to UniProt.
   
 0.933
polC
dNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.916
CCZ83637.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
 
  
 
0.908
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
  
 0.895
CCZ83026.1
Exonuclease; Product inferred by homology to UniProt.
   
 0.838
CCZ83030.1
Nucleoid-associated protein RUM_22410; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.812
CCZ83661.1
Single-stranded DNA-binding protein; Product inferred by homology to UniProt.
  
 
 
 0.790
CCZ83197.1
Single-stranded DNA-binding protein; Product inferred by homology to UniProt.
    
 
 0.757
Your Current Organism:
Ruminococcus sp. CAG254
NCBI taxonomy Id: 1262953
Other names: R. sp. CAG:254, Ruminococcus sp. CAG:254
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