STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDF07325.1Cysteine synthase; Product inferred by homology to UniProt; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)    
Predicted Functional Partners:
CDF08204.1
Serine acetyltransferase; Product inferred by homology to UniProt.
 
 0.958
cysS
cysteine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.949
CDF06375.1
Cystathionine beta-lyases/cystathionine gamma-synthases; Product inferred by homology to UniProt.
 
 0.929
CDF07878.1
Vitamin B12-dependent methionine synthase family protein; Product inferred by homology to UniProt.
    
 0.877
CDF07747.1
Pyridine nucleotide-disulfide oxidoreductase; Product inferred by homology to UniProt.
    
 0.871
rnfB
Putative uncharacterized protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
   
 
  0.789
CDF08270.1
pP-loop family protein; Product inferred by homology to UniProt; Belongs to the TtcA family.
    
 0.762
guaA
gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
 
 0.745
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.729
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.719
Your Current Organism:
Firmicutes bacterium CAG95
NCBI taxonomy Id: 1262988
Other names: F. bacterium CAG:95, Firmicutes bacterium CAG:95
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