STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDD46255.1Uncharacterized protein; Product inferred by homology to UniProt. (166 aa)    
Predicted Functional Partners:
nadE
Putative uncharacterized protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.829
CDD47536.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.820
CDD48659.1
Competence/damage-inducible domain protein CinA; Product inferred by homology to UniProt; Belongs to the CinA family.
    
  0.806
CDD48775.1
Pyruvate kinase; Product inferred by homology to UniProt; Belongs to the pyruvate kinase family.
    
  0.806
CDD46095.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
    
 0.759
CDD46771.1
Putative uncharacterized protein; Product inferred by homology to UniProt.
  
 
  0.690
CDD46254.1
Unknown; No significant homology to UniProt.
       0.671
guaA
gMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.669
CDD46253.1
aTPase; Product inferred by homology to UniProt.
       0.662
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.652
Your Current Organism:
Firmicutes bacterium CAG534
NCBI taxonomy Id: 1263027
Other names: F. bacterium CAG:534, Firmicutes bacterium CAG:534
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.