LCOR_05301.1 protein (Lichtheimia corymbifera)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Score

LCOR_05301.1

Iron-sulfur clusters transporter atm1. (685 aa)

Predicted Functional Partners:

NBP35

0.804

CFD1

0.804

LCOR_12320.1

0.774

LCOR_01384.1

0.629

LCOR_02337.1

0.629

LCOR_02266.1

0.629

LCOR_02267.1

0.629

LCOR_03650.1

0.629

LCOR_03493.1

0.629

LCOR_03838.1

0.629

Your Current Organism:

Lichtheimia corymbifera

NCBI taxonomy Id: 1263082
Other names: L. corymbifera JMRC:FSU:9682, Lichtheimia corymbifera CBS 429.75, Lichtheimia corymbifera FSU 9682, Lichtheimia corymbifera JMRC:FSU:9682

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFD1	LCOR_05301.1	A0A068SCA2	A0A068RVK2	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.	Iron-sulfur clusters transporter atm1.	0.804
CFD1	LCOR_12320.1	A0A068SCA2	A0A068SJ57	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.	Iron-sulfur protein nubpl-like.	0.423
LCOR_01384.1	LCOR_05301.1	A0A068RIV0	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_02266.1	LCOR_05301.1	A0A068RKR0	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_02267.1	LCOR_05301.1	A0A068RLH9	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_02337.1	LCOR_05301.1	A0A068RKE4	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_03493.1	LCOR_05301.1	A0A068RQI0	A0A068RVK2	Atp-binding cassette transporter.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_03650.1	LCOR_05301.1	A0A068RPN2	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_03838.1	LCOR_05301.1	A0A068RRU8	A0A068RVK2	Multidrug resistance protein 1.	Iron-sulfur clusters transporter atm1.	0.629
LCOR_05301.1	CFD1	A0A068RVK2	A0A068SCA2	Iron-sulfur clusters transporter atm1.	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.	0.804
LCOR_05301.1	LCOR_01384.1	A0A068RVK2	A0A068RIV0	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_02266.1	A0A068RVK2	A0A068RKR0	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_02267.1	A0A068RVK2	A0A068RLH9	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_02337.1	A0A068RVK2	A0A068RKE4	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_03493.1	A0A068RVK2	A0A068RQI0	Iron-sulfur clusters transporter atm1.	Atp-binding cassette transporter.	0.629
LCOR_05301.1	LCOR_03650.1	A0A068RVK2	A0A068RPN2	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_03838.1	A0A068RVK2	A0A068RRU8	Iron-sulfur clusters transporter atm1.	Multidrug resistance protein 1.	0.629
LCOR_05301.1	LCOR_12320.1	A0A068RVK2	A0A068SJ57	Iron-sulfur clusters transporter atm1.	Iron-sulfur protein nubpl-like.	0.774
LCOR_05301.1	NBP35	A0A068RVK2	A0A068RKW3	Iron-sulfur clusters transporter atm1.	Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.	0.804
LCOR_12320.1	CFD1	A0A068SJ57	A0A068SCA2	Iron-sulfur protein nubpl-like.	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.	0.423

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Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.911

expected number of edges:

10

PPI enrichment p-value:

1.35e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016114

Terpenoid biosynthetic process

8 of 12

2.42

6.7

7.87e-15

GO:0019288

Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

7 of 7

2.6

6.7

4.66e-14

GO:0090407

Organophosphate biosynthetic process

8 of 130

1.39

2.15

9.06e-09

GO:0019637

Organophosphate metabolic process

9 of 177

1.3

2.01

1.62e-09

GO:1901135

Carbohydrate derivative metabolic process

9 of 210

1.23

1.77

6.72e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016725

Oxidoreductase activity, acting on CH or CH2 groups

3 of 8

2.17

1.51

0.0013

GO:0051745

4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity

2 of 2

2.6

1.13

0.0086

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 29

1.61

0.99

0.0086

GO:0046872

Metal ion binding

7 of 488

0.75

0.52

0.0086

GO:0043167

Ion binding

9 of 894

0.6

0.43

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 250

0.9

0.53

0.0261

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4282

Isoprenoid biosynthetic process

7 of 11

2.4

5.82

8.50e-13

CL:4281

Isoprenoid metabolic process, and Carotenoid biosynthesis

8 of 21

2.18

5.54

2.10e-13

CL:4284

Isoprene biosynthesis

5 of 5

2.6

4.56

1.70e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 18

2.24

6.19

1.03e-14

map01110

Biosynthesis of secondary metabolites

9 of 542

0.82

0.78

2.19e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0414

Isoprene biosynthesis

8 of 8

2.6

7.82

1.38e-16

KW-0004

4Fe-4S

3 of 25

1.68

1.22

0.0026

KW-0479

Metal-binding

7 of 228

1.08

1.13

3.48e-05

KW-0560

Oxidoreductase

4 of 118

1.13

0.79

0.0069

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02401

LytB protein

2 of 2

2.6

0.91

0.0220

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