LCOR_05546.1 protein (Lichtheimia corymbifera)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LCOR_05546.1

Uncharacterized protein. (230 aa)

Predicted Functional Partners:

LCOR_07952.1

0.753

LCOR_07341.1

0.696

LCOR_11575.1

0.661

LCOR_12184.1

0.659

LCOR_05181.1

0.655

LCOR_08935.1

0.655

LCOR_03256.1

0.652

LCOR_06512.1

0.650

LCOR_01400.1

0.649

LCOR_11867.1

0.647

Your Current Organism:

Lichtheimia corymbifera

NCBI taxonomy Id: 1263082
Other names: L. corymbifera JMRC:FSU:9682, Lichtheimia corymbifera CBS 429.75, Lichtheimia corymbifera FSU 9682, Lichtheimia corymbifera JMRC:FSU:9682

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCOR_01400.1	LCOR_03256.1	A0A068RJ48	A0A068RNY0	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	Mitochondrial 37s ribosomal protein mrp4.	0.999
LCOR_01400.1	LCOR_05181.1	A0A068RJ48	A0A068RVX9	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	Uncharacterized protein.	0.999
LCOR_01400.1	LCOR_05546.1	A0A068RJ48	A0A068RW88	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	Uncharacterized protein.	0.649
LCOR_01400.1	LCOR_06512.1	A0A068RJ48	A0A068S0I2	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	30s ribosomal protein s16.	0.999
LCOR_01400.1	LCOR_11575.1	A0A068RJ48	A0A068SHL6	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	NDK domain-containing protein.	0.986
LCOR_01400.1	LCOR_11867.1	A0A068RJ48	A0A068SIC0	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	40s ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family.	0.999
LCOR_03256.1	LCOR_01400.1	A0A068RNY0	A0A068RJ48	Mitochondrial 37s ribosomal protein mrp4.	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	0.999
LCOR_03256.1	LCOR_05181.1	A0A068RNY0	A0A068RVX9	Mitochondrial 37s ribosomal protein mrp4.	Uncharacterized protein.	0.999
LCOR_03256.1	LCOR_05546.1	A0A068RNY0	A0A068RW88	Mitochondrial 37s ribosomal protein mrp4.	Uncharacterized protein.	0.652
LCOR_03256.1	LCOR_06512.1	A0A068RNY0	A0A068S0I2	Mitochondrial 37s ribosomal protein mrp4.	30s ribosomal protein s16.	0.999
LCOR_03256.1	LCOR_07341.1	A0A068RNY0	A0A068S1K9	Mitochondrial 37s ribosomal protein mrp4.	Uncharacterized protein.	0.568
LCOR_03256.1	LCOR_11575.1	A0A068RNY0	A0A068SHL6	Mitochondrial 37s ribosomal protein mrp4.	NDK domain-containing protein.	0.979
LCOR_03256.1	LCOR_11867.1	A0A068RNY0	A0A068SIC0	Mitochondrial 37s ribosomal protein mrp4.	40s ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family.	0.999
LCOR_05181.1	LCOR_01400.1	A0A068RVX9	A0A068RJ48	Uncharacterized protein.	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	0.999
LCOR_05181.1	LCOR_03256.1	A0A068RVX9	A0A068RNY0	Uncharacterized protein.	Mitochondrial 37s ribosomal protein mrp4.	0.999
LCOR_05181.1	LCOR_05546.1	A0A068RVX9	A0A068RW88	Uncharacterized protein.	Uncharacterized protein.	0.655
LCOR_05181.1	LCOR_06512.1	A0A068RVX9	A0A068S0I2	Uncharacterized protein.	30s ribosomal protein s16.	0.999
LCOR_05181.1	LCOR_11575.1	A0A068RVX9	A0A068SHL6	Uncharacterized protein.	NDK domain-containing protein.	0.968
LCOR_05181.1	LCOR_11867.1	A0A068RVX9	A0A068SIC0	Uncharacterized protein.	40s ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family.	0.999
LCOR_05546.1	LCOR_01400.1	A0A068RW88	A0A068RJ48	Uncharacterized protein.	S15 ns1 rna-binding domain-containing protein; Belongs to the universal ribosomal protein uS15 family.	0.649

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009097

Isoleucine biosynthetic process

7 of 14

2.26

5.34

2.79e-12

GO:0009099

Valine biosynthetic process

5 of 10

2.26

3.86

1.31e-08

GO:1901607

Alpha-amino acid biosynthetic process

10 of 104

1.55

3.16

1.07e-12

GO:0046394

Carboxylic acid biosynthetic process

11 of 166

1.39

2.55

1.07e-12

GO:0043650

Dicarboxylic acid biosynthetic process

3 of 19

1.76

1.4

0.0012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000287

Magnesium ion binding

5 of 65

1.45

1.34

0.00046

GO:0019842

Vitamin binding

4 of 46

1.5

1.14

0.0026

GO:0015930

Glutamate synthase activity

2 of 2

2.56

1.12

0.0090

GO:0004455

Ketol-acid reductoisomerase activity

2 of 2

2.56

1.12

0.0090

GO:0050661

NADP binding

3 of 22

1.7

1.01

0.0090

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005948

Acetolactate synthase complex

2 of 2

2.56

1.39

0.0028

GO:0005829

Cytosol

7 of 324

0.9

0.76

0.00080

GO:0005737

Cytoplasm

9 of 1245

0.42

0.29

0.0348

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:993

Branched-chain amino acid metabolic process

6 of 23

1.98

3.5

1.00e-08

CL:924

Branched-chain amino acid metabolic process, and Aspartate family amino acid biosynthetic process

8 of 58

1.7

3.32

2.20e-10

CL:923

Alpha-amino acid biosynthetic process, and Dicarboxylic acid metabolic process

9 of 84

1.59

3.09

5.47e-11

CL:996

Branched-chain amino acid metabolic process

4 of 17

1.94

2.12

3.68e-05

CL:810

Glutamate biosynthetic process, and Ammonia ligase activity

2 of 5

2.17

0.87

0.0239

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00290

Valine, leucine and isoleucine biosynthesis

7 of 22

2.07

4.63

1.56e-11

map00770

Pantothenate and CoA biosynthesis

6 of 21

2.02

3.94

8.68e-10

map01210

2-Oxocarboxylic acid metabolism

6 of 51

1.63

2.58

7.73e-08

map01230

Biosynthesis of amino acids

10 of 159

1.36

2.38

1.56e-11

map00660

C5-Branched dibasic acid metabolism

2 of 10

1.87

1.09

0.0074

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005948

Acetolactate synthase complex

2 of 4

2.26

1.07

0.0102

GOCC:0005737

Cytoplasm

10 of 946

0.59

0.47

0.0014

GOCC:0005622

Intracellular

11 of 1345

0.48

0.39

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0100

Branched-chain amino acid biosynthesis

4 of 14

2.02

2.3

1.87e-05

KW-0412

Isoleucine biosynthesis

2 of 3

2.39

1.26

0.0047

KW-0663

Pyridoxal phosphate

3 of 40

1.44

0.92

0.0091

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04898

Glutamate synthase central domain

2 of 2

2.56

0.85

0.0286

PF02776

Thiamine pyrophosphate enzyme, N-terminal TPP binding domain

2 of 2

2.56

0.85

0.0286

PF01645

Conserved region in glutamate synthase

2 of 2

2.56

0.85

0.0286

PF01493

GXGXG motif

2 of 2

2.56

0.85

0.0286

PF01450

Acetohydroxy acid isomeroreductase, catalytic domain

2 of 2

2.56

0.85

0.0286

(more ...)

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