STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCOR_06109.1Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (528 aa)    
Predicted Functional Partners:
LCOR_03058.1
Folic acid synthesis protein.
 
 
 0.949
LCOR_08003.1
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
     
 0.861
LCOR_09783.1
Thymidylate synthase.
     
 0.850
LCOR_11826.1
Methylenetetrahydrofolate dehydrogenase.
    
 0.838
LCOR_08632.1
Fthfs-domain-containing protein.
  
 
 0.828
LCOR_07691.1
Fthfs-domain-containing protein.
  
 
 0.828
LCOR_00567.1
Serine hydroxymethyltransferase.
  
 0.827
LCOR_04488.1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.827
LCOR_01136.1
Adp-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.
  
 
 0.808
LCOR_07023.1
Dihydrofolate reductase.
     
 0.799
Your Current Organism:
Lichtheimia corymbifera
NCBI taxonomy Id: 1263082
Other names: L. corymbifera JMRC:FSU:9682, Lichtheimia corymbifera CBS 429.75, Lichtheimia corymbifera FSU 9682, Lichtheimia corymbifera JMRC:FSU:9682
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