node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KAE1 | LCOR_00711.1 | A0A068RDL5 | A0A068RH29 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Protein cgi121; Belongs to the CGI121/TPRKB family. | 0.997 |
KAE1 | LCOR_01657.1 | A0A068RDL5 | A0A068RLU2 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Uncharacterized protein. | 0.995 |
KAE1 | LCOR_11662.1 | A0A068RDL5 | A0A068SHV2 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.647 |
KAE1 | LCOR_11813.1 | A0A068RDL5 | A0A068SFC8 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Tp53-regulating kinase-like. | 0.999 |
LCOR_00711.1 | KAE1 | A0A068RH29 | A0A068RDL5 | Protein cgi121; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.997 |
LCOR_00711.1 | LCOR_01657.1 | A0A068RH29 | A0A068RLU2 | Protein cgi121; Belongs to the CGI121/TPRKB family. | Uncharacterized protein. | 0.939 |
LCOR_00711.1 | LCOR_11662.1 | A0A068RH29 | A0A068SHV2 | Protein cgi121; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.978 |
LCOR_00711.1 | LCOR_11813.1 | A0A068RH29 | A0A068SFC8 | Protein cgi121; Belongs to the CGI121/TPRKB family. | Tp53-regulating kinase-like. | 0.998 |
LCOR_01657.1 | KAE1 | A0A068RLU2 | A0A068RDL5 | Uncharacterized protein. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.995 |
LCOR_01657.1 | LCOR_00711.1 | A0A068RLU2 | A0A068RH29 | Uncharacterized protein. | Protein cgi121; Belongs to the CGI121/TPRKB family. | 0.939 |
LCOR_01657.1 | LCOR_11662.1 | A0A068RLU2 | A0A068SHV2 | Uncharacterized protein. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.979 |
LCOR_01657.1 | LCOR_11813.1 | A0A068RLU2 | A0A068SFC8 | Uncharacterized protein. | Tp53-regulating kinase-like. | 0.943 |
LCOR_02520.1 | LCOR_11813.1 | A0A068RM62 | A0A068SFC8 | Glutaredoxin domain-containing protein. | Tp53-regulating kinase-like. | 0.581 |
LCOR_03065.1 | LCOR_11813.1 | A0A068RMS2 | A0A068SFC8 | Vacuolar atp synthase proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. | Tp53-regulating kinase-like. | 0.580 |
LCOR_10290.1 | LCOR_11813.1 | A0A068SAU5 | A0A068SFC8 | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | Tp53-regulating kinase-like. | 0.581 |
LCOR_11662.1 | KAE1 | A0A068SHV2 | A0A068RDL5 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.647 |
LCOR_11662.1 | LCOR_00711.1 | A0A068SHV2 | A0A068RH29 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Protein cgi121; Belongs to the CGI121/TPRKB family. | 0.978 |
LCOR_11662.1 | LCOR_01657.1 | A0A068SHV2 | A0A068RLU2 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Uncharacterized protein. | 0.979 |
LCOR_11662.1 | LCOR_11813.1 | A0A068SHV2 | A0A068SFC8 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Tp53-regulating kinase-like. | 0.992 |
LCOR_11813.1 | KAE1 | A0A068SFC8 | A0A068RDL5 | Tp53-regulating kinase-like. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.999 |