CCQ89158.1 protein (Nitrospina gracilis) - STRING interaction network

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Score

CCQ89158.1

Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (305 aa)

Predicted Functional Partners:

rpsK

0.764

CCQ89157.1

0.627

gcvT

0.512

dut

0.500

glyA

0.477

CCQ89153.1

0.475

CCQ91227.1

0.470

Your Current Organism:

Nitrospina gracilis

NCBI taxonomy Id: 1266370
Other names: N. gracilis 3/211, Nitrospina gracilis 3/211, Nitrospina gracilis str. 3/211, Nitrospina gracilis strain 3/211

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCQ89153.1	CCQ89158.1	NITGR_10010	NITGR_10015	Pseudouridine synthase.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.475
CCQ89157.1	CCQ89158.1	NITGR_10014	NITGR_10015	Transcriptional regulator, TetR family protein.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.627
CCQ89158.1	CCQ89153.1	NITGR_10015	NITGR_10010	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Pseudouridine synthase.	0.475
CCQ89158.1	CCQ89157.1	NITGR_10015	NITGR_10014	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Transcriptional regulator, TetR family protein.	0.627
CCQ89158.1	CCQ91227.1	NITGR_10015	NITGR_600012	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	0.470
CCQ89158.1	dut	NITGR_10015	NITGR_360092	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	0.500
CCQ89158.1	gcvT	NITGR_10015	NITGR_20037	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.	0.512
CCQ89158.1	glyA	NITGR_10015	NITGR_720015	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.477
CCQ89158.1	rpsK	NITGR_10015	NITGR_280048	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.764
CCQ91227.1	CCQ89158.1	NITGR_600012	NITGR_10015	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.470
CCQ91227.1	glyA	NITGR_600012	NITGR_720015	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.713
dut	CCQ89158.1	NITGR_360092	NITGR_10015	Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.500
gcvT	CCQ89158.1	NITGR_20037	NITGR_10015	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.512
gcvT	glyA	NITGR_20037	NITGR_720015	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.996
glyA	CCQ89158.1	NITGR_720015	NITGR_10015	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.477
glyA	CCQ91227.1	NITGR_720015	NITGR_600012	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.	0.713
glyA	gcvT	NITGR_720015	NITGR_20037	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.	0.996
rpsK	CCQ89158.1	NITGR_280048	NITGR_10015	30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.764