STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhAGlutamate dehydrogenase, NADP-specific; Function of strongly homologous gene; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa)    
Predicted Functional Partners:
gltB
Fragment of Glutamate synthase, alpha subunit (part 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.994
CCQ91335.1
Silent information regulator protein Sir2.
    
 0.903
CCQ89632.1
Putative Glutamate synthase (NADPH), large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutamate synthase family.
  
 0.883
acsA
Acetoacetyl-coenzyme A synthetase; Function of strongly homologous gene; enzyme.
   
 
 0.869
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.869
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.716
pdhA
Pyruvate dehydrogenase, E1 component, alpha subunit (acetyl-transferring); Function of strongly homologous gene; enzyme.
  
 
 0.709
pdhA-2
Pyruvate dehydrogenase, E1 component, subunit alpha; Function of strongly homologous gene; enzyme.
  
 
 0.709
CCQ91788.1
Putative Sulfite reductase (ferredoxin); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
     
 0.700
CCQ91022.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.697
Your Current Organism:
Nitrospina gracilis
NCBI taxonomy Id: 1266370
Other names: N. gracilis 3/211, Nitrospina gracilis 3/211, Nitrospina gracilis str. 3/211, Nitrospina gracilis strain 3/211
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