STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCQ91623.1Membrane hypothetical protein; No homology to any previously reported sequences. (134 aa)    
Predicted Functional Partners:
CCQ91622.1
Hypothetical protein; No homology to any previously reported sequences.
     0.994
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.732
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.604
CCQ91621.1
Hypothetical protein; No homology to any previously reported sequences.
       0.553
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.510
CCQ90968.1
Conserved exported hypothetical protein, cytochrome c554-like; Homologs of previously reported genes of unknown function.
    
  0.492
CCQ91672.1
Putative Cytochrome c-554 (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
    
  0.492
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.487
gltB
Fragment of Glutamate synthase, alpha subunit (part 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.486
purH
Bifunctional purine biosynthesis protein PurH; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.480
Your Current Organism:
Nitrospina gracilis
NCBI taxonomy Id: 1266370
Other names: N. gracilis 3/211, Nitrospina gracilis 3/211, Nitrospina gracilis str. 3/211, Nitrospina gracilis strain 3/211
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.