STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smfProtein SMF, putative DNA protecting protein DprA; Function of strongly homologous gene; phenotype. (375 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.954
CCQ92157.1
Putative Phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.937
CCQ89277.1
Putative Metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.923
yifB
Fragment of putative ATP-dependent protease, Mg chelatase-related protein (part 2); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 0.916
fliP
Flagellar biosynthetic protein FliP, export component; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
  
    0.764
CCQ89648.1
Putative FOG: CheY-like receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.733
trmFO
tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
       0.725
CCQ89584.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0758 family.
  
  
 0.653
ssb
Single-stranded DNA-binding protein; Function of homologous gene experimentally demonstrated in an other organism; cell process.
 
  
 0.645
CCQ90545.1
Exported hypothetical protein; No homology to any previously reported sequences.
  
    0.616
Your Current Organism:
Nitrospina gracilis
NCBI taxonomy Id: 1266370
Other names: N. gracilis 3/211, Nitrospina gracilis 3/211, Nitrospina gracilis str. 3/211, Nitrospina gracilis strain 3/211
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.