Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORV44352.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
    0.878
ORV44353.1
Coenzyme A pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.877
ORV44354.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.871
ORV40167.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.754
ORV40169.1
Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.729
ORV36047.1
Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.729
msrA
Methionine sulfoxide reductase B; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.723
ORV44350.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.684
LpdA
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.657
ORV45654.1
Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.657
Your Current Organism:
Mycolicibacterium doricum
NCBI taxonomy Id: 126673
Other names: CCUG 46352, CIP 106867, DSM 44339, JCM 12405, M. doricum, Mycobacterium doricum, Mycobacterium doricum Tortoli et al. 2001, Mycolicibacterium doricum (Tortoli et al., 2001) Gupta et al. 2018, strain FI-13295
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