STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BV394_03000Metallophos domain-containing protein. (381 aa)    
Predicted Functional Partners:
BV394_03005
DNA repair exonuclease SbcCD ATPase subunit.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.996
BV394_09635
ATP-dependent DNA helicase RecQ.
  
 0.994
BV394_13545
Uncharacterized protein.
    
  0.982
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.951
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.947
BV394_04775
Sodium-independent anion transporter.
   
   0.944
BV394_09460
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
    
 
 0.941
BV394_05715
DNA polymerase III delta prime subunit.
   
 0.918
BV394_02690
Cytochrome P450.
    
 0.911
Your Current Organism:
Brevirhabdus pacifica
NCBI taxonomy Id: 1267768
Other names: B. pacifica, Brevirhabdus pacifica Wu et al. 2015 emend. Liu et al. 2017, CGMCC 1.12416, DSM 27767, JCM 19489, KCTC 42421 [[Xuhuaishuia manganoxidans]], Loktanella sp. 22DY15, MCCC 1K00276, MCCC 1K00502 [[Xuhuaishuia manganoxidans]], Roseovarius sp. DY6-4, Xuhuaishuia manganoxidans, Xuhuaishuia manganoxidans Wang et al. 2016, strain 22DY15, strain DY6-4 [[Xuhuaishuia manganoxidans]]
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