STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimM16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (174 aa)    
Predicted Functional Partners:
trmD
tRNA guanine-N1-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
  
 0.989
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
  
 0.988
rplS
Ribosomal protein L19, bacterial type; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
  
 0.978
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.947
rpsB
Ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.945
rpsS
Ribosomal protein S19, bacterial/organelle; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 
 0.938
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
  
 0.936
rpsL
Ribosomal protein S12, bacterial/organelle; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
  
 0.932
rpsR
Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
   
  
 0.932
rpoA
DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.931
Your Current Organism:
Legionella oakridgensis
NCBI taxonomy Id: 1268635
Other names: L. oakridgensis ATCC 33761 = DSM 21215, Legionella oakridgensis ATCC 33761, Legionella oakridgensis ATCC 33761 = DSM 21215, Legionella oakridgensis DSM 21215, Legionella oakridgensis DSM 21215 = ATCC 33761, Legionella oakridgensis OR-10
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