STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)    
Predicted Functional Partners:
ackA
Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.956
pta
Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.947
KVA01_18390
Unannotated protein; Belongs to the aldehyde dehydrogenase family.
   
  0.942
KVA01_03800
Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
  0.941
KVA01_18540
Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
  0.941
KVA01_09930
Unannotated protein.
  
  
 
0.936
KVA01_18460
Unannotated protein.
  
 0.934
leuA
Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.933
KVA01_18520
Unannotated protein.
   
 
  0.932
prpE
Unannotated protein.
  
  
 
0.931
Your Current Organism:
Kocuria varians
NCBI taxonomy Id: 1272
Other names: ATCC 15306, CCM 884, CCUG 35392, CIP 81.73, DSM 20033, HAMBI 40, IEGM 400, IFO 15358, JCM 7238, K. varians, LMG 14231, LMG:14231, Micrococcus varians, NBRC 15358, NCDO 777, NCTC 7564
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