STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALL00529.1tRNA/RNA cytosine-C5-methylase; COG0144. (345 aa)    
Predicted Functional Partners:
ALL00528.1
Hypothetical protein.
  
 
 0.946
ALL00527.1
Putative FKBP-type peptidyl-prolyl cis-trans isomerase; COG1047.
       0.861
thiI
Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
    0.723
ALL01677.1
GTP-binding protein; COG1161; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 
 0.718
ALL00532.1
GTP-binding protein; COG1084.
   
 
 0.711
ALL00618.1
rRNA biogenesis protein Nop56/Nop58; COG1498.
  
 
 0.680
rtcA
RNA 3'-terminal-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
 
 0.661
eif6
Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
   
 
 0.609
rps8e
30S ribosomal protein S8e; COG2007.
   
 
 0.605
ALL02033.1
Hypothetical protein; Probably involved in the biogenesis of the ribosome.
   
 
 0.593
Your Current Organism:
Pyrodictium delaneyi
NCBI taxonomy Id: 1273541
Other names: ATCC BAA-2559, DSM 28599, Hyperthermus sp. Su06, P. delaneyi, Pyrodictium delaneyi Lin et al. 2016, Pyrodictium sp. Su06, strain Su06
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.