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fumC protein (Dermacoccus nishinomiyaensis) - STRING interaction network
"fumC" - Fumarate hydratase class II in Dermacoccus nishinomiyaensis
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (465 aa)    
Predicted Functional Partners:
HX89_10625
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method- Protein Homology (234 aa)
     
  0.989
HX89_03965
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (577 aa)
   
 
  0.980
gltA
Citrate synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the citrate [...] (421 aa)
   
  0.980
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (327 aa)
   
  0.977
sdhA
Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method- Protein Homology (691 aa)
   
  0.975
HX89_10615
Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family (246 aa)
   
  0.970
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method- Protein Homology (1278 aa)
   
 
  0.962
mqo
Probable malate-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method- Protein Homology (498 aa)
   
 
  0.933
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily (723 aa)
   
 
  0.918
HX89_09680
Malate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the malate synthase family (545 aa)
   
 
  0.918
Your Current Organism:
Dermacoccus nishinomiyaensis
NCBI taxonomy Id: 1274
Other names: ATCC 29093, CCM 2140, CCUG 33028, CIP 81.71, D. nishinomiyaensis, DSM 20448, Dermacoccus nishinomiyaensis, Dermacoccus nishinomiyensis, Dermatococcus nishinomiyaensis, Dermatococcus nishinomiyensis, IEGM 393, IFO 15356, JCM 11613, LMG 14222, Micrococcus nishinomiyaensis, Micrococcus nishinomyaensis, NBRC 15356, NCTC 11039
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