STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101344608Pappalysin-1. (1420 aa)    
Predicted Functional Partners:
LOC101341479
Insulin-like growth factor-binding protein 5.
    
 0.769
LOC101350941
Stanniocalcin-2.
    
 
 0.742
LOC101342131
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
    
 
 0.719
LOC101357931
Bone marrow proteoglycan isoform X1.
    
 0.706
LOC101357677
Proteoglycan 3.
    
 0.706
LOC101361970
Interferon gamma receptor 2.
      
 0.620
LOC101361934
Insulin-like growth factor I isoform X1.
     
 0.590
LOC101350889
Adipocyte plasma membrane-associated protein isoform X1.
      
 0.569
LOC101343877
Galectin.
   
  
 0.556
LOC101342251
Insulin-like growth factor-binding protein 4.
    
 0.511
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.