STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101350706Deoxyribonuclease; Belongs to the DNase I family. (278 aa)    
Predicted Functional Partners:
LOC101346965
Regulating synaptic membrane exocytosis protein 2 isoform X21.
   
 
 0.496
LOC101341290
Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.
   
 0.467
LOC101344779
Inhibitor of nuclear factor kappa-B kinase subunit epsilon.
   
 0.467
LOC101345902
Serine/threonine-protein kinase TBK1 isoform X1.
   
 0.467
LOC101351256
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.
   
 0.467
LOC101345416
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
      
 0.434
LOC101342900
Deoxyribonuclease-2-alpha.
      
 0.434
LOC101351710
rab-3A-interacting protein.
      
 0.428
LOC101359028
Phospholipase A(2).
   
    0.416
LOC101346018
Ragulator complex protein LAMTOR2.
    
 0.414
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.