STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101350055E3 ubiquitin-protein ligase UBR4 isoform X1. (5185 aa)    
Predicted Functional Partners:
LOC101346788
E3 ubiquitin-protein ligase KCMF1.
    
 
 0.902
LOC101349626
ER membrane protein complex subunit 1 isoform X1.
 
    
 0.690
LOC101351365
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
 
 0.677
LOC101360460
E3 ubiquitin-protein ligase HUWE1.
   
 
 0.635
LOC101361121
LOW QUALITY PROTEIN: calmodulin-like protein 6.
    
 
 0.590
LOC101346473
Calmodulin-like protein 4.
    
 
 0.590
LOC101356120
LOW QUALITY PROTEIN: bifunctional glutamate/proline--tRNA ligase.
      
 0.581
LOC101357460
Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.
      
 0.574
LOC101349373
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
      
 0.551
LOC101347000
DNA mismatch repair protein Mlh1.
      
 0.550
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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