STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101357815Serine/threonine-protein kinase WNK1 isoform X6. (2638 aa)    
Predicted Functional Partners:
LOC101342779
Kelch-like protein 3.
    
 
 0.721
LOC101360817
Kelch-like protein 2 isoform X1.
    
 
 0.656
LOC101354056
Solute carrier family 12 member 3 isoform X1.
    
 
 0.619
LOC101341335
ATP-sensitive inward rectifier potassium channel 1.
    
 
 0.615
LOC101341482
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.602
LOC101349474
Mediator of RNA polymerase II transcription subunit 17.
    
 
 0.602
LOC101348491
Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.
    
 
 0.563
LOC101361653
Transcription factor AP-1; Belongs to the bZIP family.
    
 
 0.558
LOC101356278
Transcription factor jun-B.
    
 
 0.558
LOC101350224
Transcription factor jun-D.
    
 
 0.558
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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