STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101353606Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)    
Predicted Functional Partners:
LOC101354516
Hedgehog-interacting protein.
    
 0.996
LOC101346502
Protein patched homolog 1 isoform X1.
   
 0.991
LOC101354158
Protein patched homolog 2.
   
 0.990
LOC101344305
Cell adhesion molecule-related/down-regulated by oncogenes.
    
 0.989
LOC101350880
Brother of CDO.
    
 0.988
LOC101351951
Growth arrest-specific protein 1.
    
 0.953
LOC101351744
LOW QUALITY PROTEIN: sonic hedgehog protein.
  
  
0.943
LOC101348175
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
  
0.942
LOC101342744
Low-density lipoprotein receptor-related protein 2.
     
 0.913
LOC101342163
Protein dispatched homolog 1 isoform X1.
   
 0.857
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (28%) [HD]