STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101354722Serine/threonine kinase-like domain-containing protein STKLD1. (704 aa)    
Predicted Functional Partners:
LOC101345024
Pseudokinase FAM20A.
     
 0.701
LOC101345730
Tyrosine-protein kinase PRAG1.
      
 0.670
LOC101352301
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
      
 0.596
LOC101361611
Uncharacterized protein PEAK3.
      
 0.432
LOC101342236
Pseudopodium-enriched atypical kinase 1.
      
 0.432
LOC101349618
Serine/threonine-protein kinase Nek7 isoform X1; Belongs to the protein kinase superfamily.
    
0.423
LOC101359361
Serine/threonine-protein kinase Nek6 isoform X1; Belongs to the protein kinase superfamily.
    
0.423
LOC101344001
Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily.
   
 
0.402
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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