STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101358738Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (473 aa)    
Predicted Functional Partners:
LOC101355156
Metabotropic glutamate receptor 4 isoform X1.
   
  
 0.707
LOC101340315
Transcription factor GATA-4 isoform X1.
    
 
 0.639
LOC101342738
Multiple PDZ domain protein isoform X1.
   
  
 0.547
LOC101344544
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
   
 
0.546
LOC101348846
Transducin-like enhancer protein 3 isoform X1.
      
 0.476
LOC101357043
semaphorin-6A isoform X1; Belongs to the semaphorin family.
      
 0.463
LOC101358099
Transcription factor GATA-6.
    
 
 0.439
LOC101358325
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2; Belongs to the 3-beta-HSD family.
      
 0.429
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
Server load: low (18%) [HD]