STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC1013477315'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (292 aa)    
Predicted Functional Partners:
LOC101354022
5'(3')-deoxyribonucleotidase, mitochondrial.
     
 0.923
LOC101355585
Cytosolic 5'-nucleotidase 1A.
     
 0.920
LOC101350421
Deoxyguanosine kinase, mitochondrial isoform X1.
   
 
 0.919
LOC101344787
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.919
LOC101361423
Uridine 5'-monophosphate synthase isoform X1.
     
 0.918
LOC101357298
Adenine phosphoribosyltransferase isoform X1.
     
 0.918
LOC101353804
5'(3')-deoxyribonucleotidase, cytosolic type.
     
 0.916
LOC101345228
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
     
 0.914
LOC101351532
Thymidylate kinase isoform X1.
   
 
 0.911
LOC101359957
UMP-CMP kinase 2, mitochondrial isoform X1.
   
 
 0.910
Your Current Organism:
Trichechus manatus
NCBI taxonomy Id: 127582
Other names: Florida manatee, T. manatus latirostris, Trichechus manatus latirostris
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