node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acpP | gcvH | ADICEAN_01778 | ADICEAN_00305 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.912 |
acpP | glyA | ADICEAN_01778 | ADICEAN_00490 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.404 |
acpP | lipB | ADICEAN_01778 | ADICEAN_00696 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.901 |
gcvH | acpP | ADICEAN_00305 | ADICEAN_01778 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.912 |
gcvH | gcvP_1 | ADICEAN_00305 | ADICEAN_02524 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; Overlaps CDS with the same product name. | 0.999 |
gcvH | gcvP_2 | ADICEAN_00305 | ADICEAN_02525 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; Overlaps CDS with the same product name; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | ADICEAN_00305 | ADICEAN_02754 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH | glyA | ADICEAN_00305 | ADICEAN_00490 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.975 |
gcvH | lipA | ADICEAN_00305 | ADICEAN_03867 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.941 |
gcvH | lipB | ADICEAN_00305 | ADICEAN_00696 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.913 |
gcvH | lpd_1 | ADICEAN_00305 | ADICEAN_00825 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.976 |
gcvH | lpd_2 | ADICEAN_00305 | ADICEAN_01009 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.977 |
gcvH | sucA | ADICEAN_00305 | ADICEAN_01007 | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate dehydrogenase E1 component. | 0.920 |
gcvP_1 | gcvH | ADICEAN_02524 | ADICEAN_00305 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Octanoyl/lipoyl carrier protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvP_1 | gcvP_2 | ADICEAN_02524 | ADICEAN_02525 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Glycine dehydrogenase; Overlaps CDS with the same product name; Belongs to the GcvP family. | 0.999 |
gcvP_1 | gcvT | ADICEAN_02524 | ADICEAN_02754 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvP_1 | glyA | ADICEAN_02524 | ADICEAN_00490 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Pyridoxal-phosphate-dependent serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.987 |
gcvP_1 | lipA | ADICEAN_02524 | ADICEAN_03867 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.413 |
gcvP_1 | lipB | ADICEAN_02524 | ADICEAN_00696 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.423 |
gcvP_1 | lpd_1 | ADICEAN_02524 | ADICEAN_00825 | Glycine dehydrogenase; Overlaps CDS with the same product name. | Dihydrolipoyl dehydrogenase. | 0.896 |