mutS_3 protein (Cesiribacter andamanensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mutS_3

DNA mismatch repair protein mutS. (629 aa)

Predicted Functional Partners:

dnaN

0.990

mutL_2

0.990

polA

0.990

mutL_1

0.988

recQ_4

0.773

anmK

0.746

mutS_1

0.632

gluD

0.624

mutS2

0.612

mutS_2

0.537

Your Current Organism:

Cesiribacter andamanensis

NCBI taxonomy Id: 1279009
Other names: C. andamanensis AMV16, Cesiribacter andamanensis AMV16, Flexibacter sp. AMV16

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
anmK	gluD	ADICEAN_01075	ADICEAN_01076	Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	NAD-specific glutamate dehydrogenase.	0.686
anmK	mutS_3	ADICEAN_01075	ADICEAN_01074	Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	DNA mismatch repair protein mutS.	0.746
dnaN	mutL_1	ADICEAN_01329	ADICEAN_03598	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	0.934
dnaN	mutL_2	ADICEAN_01329	ADICEAN_03599	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein mutL; Overlaps CDS with the same product name; Belongs to the DNA mismatch repair MutL/HexB family.	0.934
dnaN	mutS_1	ADICEAN_01329	ADICEAN_01052	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein mutS; Overlaps CDS with the same product name.	0.992
dnaN	mutS_2	ADICEAN_01329	ADICEAN_01053	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein mutS; Overlaps CDS with the same product name; Belongs to the DNA mismatch repair MutS family.	0.992
dnaN	mutS_3	ADICEAN_01329	ADICEAN_01074	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein mutS.	0.990
dnaN	polA	ADICEAN_01329	ADICEAN_03706	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.999
dnaN	recQ_4	ADICEAN_01329	ADICEAN_02784	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	ATP-dependent DNA helicase recQ.	0.992
gluD	anmK	ADICEAN_01076	ADICEAN_01075	NAD-specific glutamate dehydrogenase.	Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.686
gluD	mutS_3	ADICEAN_01076	ADICEAN_01074	NAD-specific glutamate dehydrogenase.	DNA mismatch repair protein mutS.	0.624
mutL_1	dnaN	ADICEAN_03598	ADICEAN_01329	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.934
mutL_1	mutL_2	ADICEAN_03598	ADICEAN_03599	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA mismatch repair protein mutL; Overlaps CDS with the same product name; Belongs to the DNA mismatch repair MutL/HexB family.	0.996
mutL_1	mutS2	ADICEAN_03598	ADICEAN_02154	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.	0.559
mutL_1	mutS_1	ADICEAN_03598	ADICEAN_01052	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA mismatch repair protein mutS; Overlaps CDS with the same product name.	0.995
mutL_1	mutS_2	ADICEAN_03598	ADICEAN_01053	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA mismatch repair protein mutS; Overlaps CDS with the same product name; Belongs to the DNA mismatch repair MutS family.	0.995
mutL_1	mutS_3	ADICEAN_03598	ADICEAN_01074	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA mismatch repair protein mutS.	0.988
mutL_1	polA	ADICEAN_03598	ADICEAN_03706	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.991
mutL_1	recQ_4	ADICEAN_03598	ADICEAN_02784	DNA mismatch repair protein mutL; Overlaps CDS with the same product name.	ATP-dependent DNA helicase recQ.	0.874
mutL_2	dnaN	ADICEAN_03599	ADICEAN_01329	DNA mismatch repair protein mutL; Overlaps CDS with the same product name; Belongs to the DNA mismatch repair MutL/HexB family.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.934