node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EMR01622.1 | EMR03006.1 | ADICEAN_03244 | ADICEAN_01855 | Eukaryotic DNA topoisomerase I, catalytic core. | Putative 3'-5' exonuclease; Related to the exonuclease domain of PolB. | 0.468 |
EMR01622.1 | dnaN | ADICEAN_03244 | ADICEAN_01329 | Eukaryotic DNA topoisomerase I, catalytic core. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.440 |
EMR01622.1 | rnhB | ADICEAN_03244 | ADICEAN_01430 | Eukaryotic DNA topoisomerase I, catalytic core. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.914 |
EMR02664.1 | acpP | ADICEAN_02203 | ADICEAN_01778 | Hypothetical protein. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.970 |
EMR02664.1 | rnhB | ADICEAN_02203 | ADICEAN_01430 | Hypothetical protein. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.737 |
EMR03006.1 | EMR01622.1 | ADICEAN_01855 | ADICEAN_03244 | Putative 3'-5' exonuclease; Related to the exonuclease domain of PolB. | Eukaryotic DNA topoisomerase I, catalytic core. | 0.468 |
EMR03006.1 | dnaN | ADICEAN_01855 | ADICEAN_01329 | Putative 3'-5' exonuclease; Related to the exonuclease domain of PolB. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.997 |
EMR03006.1 | rnhB | ADICEAN_01855 | ADICEAN_01430 | Putative 3'-5' exonuclease; Related to the exonuclease domain of PolB. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.841 |
acpP | EMR02664.1 | ADICEAN_01778 | ADICEAN_02203 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Hypothetical protein. | 0.970 |
acpP | dnaN | ADICEAN_01778 | ADICEAN_01329 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.438 |
acpP | puuB | ADICEAN_01778 | ADICEAN_02964 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Gamma-glutamylputrescine oxidoreductase. | 0.977 |
acpP | rnhB | ADICEAN_01778 | ADICEAN_01430 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.879 |
dnaN | EMR01622.1 | ADICEAN_01329 | ADICEAN_03244 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Eukaryotic DNA topoisomerase I, catalytic core. | 0.440 |
dnaN | EMR03006.1 | ADICEAN_01329 | ADICEAN_01855 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative 3'-5' exonuclease; Related to the exonuclease domain of PolB. | 0.997 |
dnaN | acpP | ADICEAN_01329 | ADICEAN_01778 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.438 |
dnaN | rnhA | ADICEAN_01329 | ADICEAN_03346 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family. | 0.596 |
dnaN | rnhB | ADICEAN_01329 | ADICEAN_01430 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.974 |
dnaN | thyA | ADICEAN_01329 | ADICEAN_04129 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.862 |
lpxB | rnhB | ADICEAN_01465 | ADICEAN_01430 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.970 |
pgcA | rnhB | ADICEAN_01382 | ADICEAN_01430 | Phosphoglucomutase. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.741 |