EMR02024.1 protein (Cesiribacter andamanensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

EMR02024.1

ComEC family competence protein. (689 aa)

Predicted Functional Partners:

EMR02896.1

0.898

EMR04620.1

0.865

comM

0.787

EMR03517.1

0.698

mscS_4

0.549

arcB_3

0.541

EMR04170.1

0.537

EMR02796.1

0.501

EMR04286.1

0.498

EMR02026.1

0.485

Your Current Organism:

Cesiribacter andamanensis

NCBI taxonomy Id: 1279009
Other names: C. andamanensis AMV16, Cesiribacter andamanensis AMV16, Flexibacter sp. AMV16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EMR02024.1	EMR02026.1	ADICEAN_02848	ADICEAN_02850	ComEC family competence protein.	Hypothetical protein.	0.485
EMR02024.1	EMR02796.1	ADICEAN_02848	ADICEAN_02071	ComEC family competence protein.	Hypothetical protein.	0.501
EMR02024.1	EMR02896.1	ADICEAN_02848	ADICEAN_01934	ComEC family competence protein.	DNA utilization protein GntX.	0.898
EMR02024.1	EMR03517.1	ADICEAN_02848	ADICEAN_01366	ComEC family competence protein.	Hybrid sensory histidine kinase BarA.	0.698
EMR02024.1	EMR04170.1	ADICEAN_02848	ADICEAN_00694	ComEC family competence protein.	Hypothetical protein; Belongs to the UPF0102 family.	0.537
EMR02024.1	EMR04286.1	ADICEAN_02848	ADICEAN_00572	ComEC family competence protein.	comEA protein.	0.498
EMR02024.1	EMR04620.1	ADICEAN_02848	ADICEAN_00222	ComEC family competence protein.	Hypothetical protein.	0.865
EMR02024.1	arcB_3	ADICEAN_02848	ADICEAN_01683	ComEC family competence protein.	Aerobic respiration control sensor protein ArcB.	0.541
EMR02024.1	comM	ADICEAN_02848	ADICEAN_03904	ComEC family competence protein.	Competence protein ComM.	0.787
EMR02024.1	mscS_4	ADICEAN_02848	ADICEAN_02849	ComEC family competence protein.	Small-conductance mechanosensitive channel.	0.549
EMR02026.1	EMR02024.1	ADICEAN_02850	ADICEAN_02848	Hypothetical protein.	ComEC family competence protein.	0.485
EMR02026.1	mscS_4	ADICEAN_02850	ADICEAN_02849	Hypothetical protein.	Small-conductance mechanosensitive channel.	0.675
EMR02796.1	EMR02024.1	ADICEAN_02071	ADICEAN_02848	Hypothetical protein.	ComEC family competence protein.	0.501
EMR02796.1	EMR04286.1	ADICEAN_02071	ADICEAN_00572	Hypothetical protein.	comEA protein.	0.584
EMR02896.1	EMR02024.1	ADICEAN_01934	ADICEAN_02848	DNA utilization protein GntX.	ComEC family competence protein.	0.898
EMR02896.1	EMR03517.1	ADICEAN_01934	ADICEAN_01366	DNA utilization protein GntX.	Hybrid sensory histidine kinase BarA.	0.818
EMR02896.1	EMR04170.1	ADICEAN_01934	ADICEAN_00694	DNA utilization protein GntX.	Hypothetical protein; Belongs to the UPF0102 family.	0.723
EMR02896.1	EMR04286.1	ADICEAN_01934	ADICEAN_00572	DNA utilization protein GntX.	comEA protein.	0.410
EMR02896.1	EMR04620.1	ADICEAN_01934	ADICEAN_00222	DNA utilization protein GntX.	Hypothetical protein.	0.882
EMR02896.1	arcB_3	ADICEAN_01934	ADICEAN_01683	DNA utilization protein GntX.	Aerobic respiration control sensor protein ArcB.	0.557

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.89

expected number of edges:

18

PPI enrichment p-value:

9.7e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 296

1.51

2.89

9.61e-12

GO:0000028

Ribosomal small subunit assembly

2 of 7

2.43

1.32

0.0037

GO:0009987

Cellular process

11 of 5102

0.31

0.25

0.0328

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 153

1.75

3.85

2.64e-12

GO:0019843

rRNA binding

4 of 57

1.82

1.87

0.00010

GO:0003723

RNA binding

7 of 497

1.13

1.15

6.47e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 167

1.71

3.71

2.68e-12

GO:0044391

Ribosomal subunit

7 of 94

1.85

3.61

5.78e-10

GO:0015935

Small ribosomal subunit

5 of 37

2.11

3.38

6.83e-08

GO:0022626

Cytosolic ribosome

3 of 56

1.71

1.31

0.0017

GO:0022627

Cytosolic small ribosomal subunit

2 of 18

2.02

1.09

0.0083

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:23734264

(2013) Complete sequence and analysis of plastid genomes of two economically important red algae: Pyropia haitanensis and Pyropia yezoensis.

3 of 38

1.88

1.09

0.0072

PMID:20502706

(2010) The complete plastid genomes of the two dinotoms Durinskia baltica and Kryptoperidinium foliaceum.

3 of 43

1.82

1.08

0.0072

PMID:20333213

(2009) The complete plastid genome sequence of the secondarily nonphotosynthetic alga Cryptomonas paramecium: reduction, compaction, and accelerated evolutionary rate.

3 of 53

1.73

1.06

0.0072

PMID:26780836

(2016) Algorithms for reconstruction of chromosomal structures.

3 of 63

1.66

1.03

0.0076

PMID:34966403

(2021) Chloroplast Genomes for Five Skeletonema Species: Comparative and Phylogenetic Analysis.

3 of 92

1.49

0.82

0.0180

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:543

Ribosome, and RRF superfamily

5 of 57

1.92

2.79

5.94e-07

CL:276

GTP hydrolysis and joining of the 60S ribosomal subunit, and rRNA-binding

6 of 101

1.75

2.55

5.94e-07

CL:283

Ribosome

4 of 74

1.71

1.75

0.00012

CL:568

Mixed, incl. L28p-like, and Ribosomal protein L9

2 of 6

2.5

1.42

0.0024

CL:555

Ribosome

3 of 42

1.83

1.41

0.0013

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pti03010

Ribosome

5 of 91

1.72

2.3

2.77e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

7 of 241

1.44

1.96

9.37e-07

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

3 of 85

1.53

0.81

0.0209

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

3 of 81

1.55

0.81

0.0209

MAP-975957

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

3 of 91

1.5

0.8

0.0209

MAP-927802

Nonsense-Mediated Decay (NMD)

3 of 91

1.5

0.8

0.0209

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009536

Plastid

5 of 195

1.39

1.24

0.00069

GOCC:0005840

Ribosome

3 of 64

1.65

1.08

0.0054

GOCC:0009507

Chloroplast

4 of 149

1.41

1.06

0.0030

GOCC:0005737

Cytoplasm

10 of 2342

0.61

0.49

0.00097

GOCC:0043229

Intracellular organelle

10 of 3005

0.5

0.38

0.0054

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 91

1.72

2.2

5.80e-06

KW-0699

rRNA-binding

2 of 32

1.77

0.75

0.0353

KW-0694

RNA-binding

3 of 151

1.28

0.65

0.0353

KW-0150

Chloroplast

3 of 174

1.21

0.63

0.0353

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00177

Ribosomal protein S7p/S5e

2 of 2

2.98

1.22

0.0063

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036823

Ribosomal protein S7 domain superfamily

2 of 2

2.98

0.97

0.0180

IPR023798

Ribosomal protein S7 domain

2 of 2

2.98

0.97

0.0180

IPR020606

Ribosomal protein S7, conserved site

2 of 2

2.98

0.97

0.0180

IPR000235

Ribosomal protein S5/S7

2 of 2

2.98

0.97

0.0180

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