STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xecD12-(R)-hydroxypropyl-CoM dehydrogenase. (261 aa)    
Predicted Functional Partners:
AXFE_01530
Putative short-chain type dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
    
0.926
gltB2
Glutamate synthase [NADPH] large chain.
     
 0.841
bfmBAA
2-oxoisovalerate dehydrogenase subunit alpha.
   
 0.801
bglF
PTS system beta-glucoside-specific EIIBCA component.
     
 0.795
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.751
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.648
pksC
Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC.
 
 0.639
accB
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
  0.638
pcaF1
beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  0.628
accC1
Biotin carboxylase.
  
 
  0.592
Your Current Organism:
Acidithrix ferrooxidans
NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3
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