STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AXFE_07050PD-(D/E)XK nuclease superfamily protein. (281 aa)    
Predicted Functional Partners:
uvrD2
ATP-dependent DNA helicase UvrD2.
   
  0.905
AXFE_07060
PAP2 superfamily protein.
       0.760
uvrD11
ATP-dependent DNA helicase UvrD1.
   
  0.690
uvrD12
ATP-dependent DNA helicase UvrD1.
   
  0.690
AXFE_31300
Hypothetical protein.
 
   0.684
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
   
 0.633
pimA
GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase.
  
     0.610
AXFE_34730
AP-4-A phosphorylase.
    
  0.599
dop
Depupylase.
 
     0.575
AXFE_09820
Phosphatidylinositol mannoside acyltransferase.
  
     0.573
Your Current Organism:
Acidithrix ferrooxidans
NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3
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