STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prcA2Proteasome subunit alpha 2; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (226 aa)    
Predicted Functional Partners:
prcB
Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 0.999
arc
Proteasome-associated ATPase.
 
 0.999
AXFE_01210
Hypothetical protein.
  
 
 
 0.991
pup
Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
 
 
 0.983
pafA
Pup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
   
 0.979
mec
CysO-cysteine peptidase.
   
 0.974
glpK1
Glycerol kinase; Belongs to the FGGY kinase family.
   
 0.948
glpK2
Glycerol kinase.
   
 0.948
dop
Depupylase.
   
 0.890
spoVK
Stage V sporulation protein K.
   
 0.759
Your Current Organism:
Acidithrix ferrooxidans
NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.