STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AXFE_11570Subtilase family protein. (747 aa)    
Predicted Functional Partners:
ftsH1
ATP-dependent zinc metalloprotease FtsH.
 
  
 0.956
pknD
Serine/threonine-protein kinase PknD.
 
 0.805
pmpB
Putative outer membrane protein PmpB precursor.
  
 0.778
AXFE_04880
NHL repeat protein.
  
 0.778
yerB
Putative lipoprotein YerB precursor.
  
 0.778
AXFE_23400
Hypothetical protein.
  
 0.778
AXFE_36810
Fibronectin type III domain protein.
  
 0.778
secY
Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.765
AXFE_25960
Hypothetical protein.
  
 
 0.676
AXFE_34730
AP-4-A phosphorylase.
     
 0.661
Your Current Organism:
Acidithrix ferrooxidans
NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.