STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polSSorbitol dehydrogenase. (327 aa)    
Predicted Functional Partners:
gltB2
Glutamate synthase [NADPH] large chain.
     
 0.841
bfmBAA
2-oxoisovalerate dehydrogenase subunit alpha.
   
 0.801
bglF
PTS system beta-glucoside-specific EIIBCA component.
     
 0.795
adhD
Putative alcohol dehydrogenase D.
   
 0.757
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.751
fabF
3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.641
pksC
Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC.
  
 0.607
pfkB
6-phosphofructokinase isozyme 2; Belongs to the carbohydrate kinase PfkB family.
   
 
  0.582
cypB
Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
   0.564
AXFE_29000
Putative oxidoreductase/MSMEI_1564.
   
 0.563
Your Current Organism:
Acidithrix ferrooxidans
NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3
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