tldD protein (Acidithrix ferrooxidans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tldD

Metalloprotease TldD. (463 aa)

Predicted Functional Partners:

pmbA

0.881

ycdX

0.783

coaE

0.623

lpdA

0.520

cbiF

0.519

nfo

0.519

Your Current Organism:

Acidithrix ferrooxidans

NCBI taxonomy Id: 1280514
Other names: A. ferrooxidans, DSM 28176, JCM 19728, acid streamer bacterium Py-F3, strain PY-F3

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbiF	lpdA	AXFE_10070	AXFE_07470	Cobalt-precorrin-4 C(11)-methyltransferase.	NAD(P)H dehydrogenase (quinone).	0.521
cbiF	nfo	AXFE_10070	AXFE_10370	Cobalt-precorrin-4 C(11)-methyltransferase.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.521
cbiF	tldD	AXFE_10070	AXFE_20960	Cobalt-precorrin-4 C(11)-methyltransferase.	Metalloprotease TldD.	0.519
coaE	tldD	AXFE_20890	AXFE_20960	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Metalloprotease TldD.	0.623
lpdA	cbiF	AXFE_07470	AXFE_10070	NAD(P)H dehydrogenase (quinone).	Cobalt-precorrin-4 C(11)-methyltransferase.	0.521
lpdA	nfo	AXFE_07470	AXFE_10370	NAD(P)H dehydrogenase (quinone).	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.520
lpdA	tldD	AXFE_07470	AXFE_20960	NAD(P)H dehydrogenase (quinone).	Metalloprotease TldD.	0.520
nfo	cbiF	AXFE_10370	AXFE_10070	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Cobalt-precorrin-4 C(11)-methyltransferase.	0.521
nfo	lpdA	AXFE_10370	AXFE_07470	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	NAD(P)H dehydrogenase (quinone).	0.520
nfo	tldD	AXFE_10370	AXFE_20960	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Metalloprotease TldD.	0.519
pmbA	tldD	AXFE_20950	AXFE_20960	Metalloprotease PmbA.	Metalloprotease TldD.	0.881
pmbA	ycdX	AXFE_20950	AXFE_20940	Metalloprotease PmbA.	Phosphatase YcdX.	0.783
tldD	cbiF	AXFE_20960	AXFE_10070	Metalloprotease TldD.	Cobalt-precorrin-4 C(11)-methyltransferase.	0.519
tldD	coaE	AXFE_20960	AXFE_20890	Metalloprotease TldD.	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.623
tldD	lpdA	AXFE_20960	AXFE_07470	Metalloprotease TldD.	NAD(P)H dehydrogenase (quinone).	0.520
tldD	nfo	AXFE_20960	AXFE_10370	Metalloprotease TldD.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.519
tldD	pmbA	AXFE_20960	AXFE_20950	Metalloprotease TldD.	Metalloprotease PmbA.	0.881
tldD	ycdX	AXFE_20960	AXFE_20940	Metalloprotease TldD.	Phosphatase YcdX.	0.783
ycdX	pmbA	AXFE_20940	AXFE_20950	Phosphatase YcdX.	Metalloprotease PmbA.	0.783
ycdX	tldD	AXFE_20940	AXFE_20960	Phosphatase YcdX.	Metalloprotease TldD.	0.783