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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sarRAccessory regulator A; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)    
Predicted Functional Partners:
BEK99_02085
Luciferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.611
ldh_2
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily.
   
  
 0.520
sarZ_1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.506
clpC
ATP-dependent Clp protease ATP-binding subunit ClpC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
   
  
 0.506
sigB
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
      
 0.503
ccpA_2
Catabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.492
sarV_1
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.476
sarV_2
MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.473
srrA
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.425
spxA
Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
   
    0.422
Your Current Organism:
Staphylococcus carnosus
NCBI taxonomy Id: 1281
Other names: ATCC 51365, CCUG 15605, CIP 103274, DSM 20501, NCTC 13825, NRRL B-14760, S. carnosus, strain 361
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