node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKC75273.1 | AKC75955.1 | ShL2_00393 | ShL2_01092 | N-succinyldiaminopimelate aminotransferase. | GAF domain-containing protein. | 0.900 |
AKC75273.1 | AKC76925.1 | ShL2_00393 | ShL2_02072 | N-succinyldiaminopimelate aminotransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.905 |
AKC75273.1 | metE | ShL2_00393 | ShL2_02434 | N-succinyldiaminopimelate aminotransferase. | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.906 |
AKC75273.1 | metH | ShL2_00393 | ShL2_02433 | N-succinyldiaminopimelate aminotransferase. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.947 |
AKC75273.1 | metK | ShL2_00393 | ShL2_01023 | N-succinyldiaminopimelate aminotransferase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.925 |
AKC75888.1 | metK | ShL2_01024 | ShL2_01023 | Hypothetical protein. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.804 |
AKC75955.1 | AKC75273.1 | ShL2_01092 | ShL2_00393 | GAF domain-containing protein. | N-succinyldiaminopimelate aminotransferase. | 0.900 |
AKC75955.1 | AKC76925.1 | ShL2_01092 | ShL2_02072 | GAF domain-containing protein. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.900 |
AKC75955.1 | metE | ShL2_01092 | ShL2_02434 | GAF domain-containing protein. | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
AKC75955.1 | metH | ShL2_01092 | ShL2_02433 | GAF domain-containing protein. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.902 |
AKC75955.1 | metK | ShL2_01092 | ShL2_01023 | GAF domain-containing protein. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
AKC76925.1 | AKC75273.1 | ShL2_02072 | ShL2_00393 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | N-succinyldiaminopimelate aminotransferase. | 0.905 |
AKC76925.1 | AKC75955.1 | ShL2_02072 | ShL2_01092 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | GAF domain-containing protein. | 0.900 |
AKC76925.1 | metE | ShL2_02072 | ShL2_02434 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.933 |
AKC76925.1 | metH | ShL2_02072 | ShL2_02433 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase. | 0.997 |
AKC76925.1 | metK | ShL2_02072 | ShL2_01023 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.959 |
coaBC | metK | ShL2_01635 | ShL2_01023 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.798 |
metE | AKC75273.1 | ShL2_02434 | ShL2_00393 | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | N-succinyldiaminopimelate aminotransferase. | 0.906 |
metE | AKC75955.1 | ShL2_02434 | ShL2_01092 | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | GAF domain-containing protein. | 0.900 |
metE | AKC76925.1 | ShL2_02434 | ShL2_02072 | 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.933 |