STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrA-2Peptide methionine sulfoxide reductase II; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (175 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase MsrB.
 
 0.999
crr
Phosphotransferase system glucose-specific IIA component.
       0.864
AKC76231.1
Hypothetical protein; Belongs to the UPF0346 family.
       0.864
blaZ
Beta-lactamase precursor, BlaZ.
     
 0.836
norA
multidrug/H+ antiporter.
      
 0.833
dfrA_2
Trimethoprim-sensitive dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.827
AKC76227.1
Fatty acid-binding protein, DegV family.
       0.788
AKC76233.1
GNAT family acetyltransferase.
      0.786
AKC76232.1
Serine protease; Belongs to the peptidase S41A family.
 
    0.772
gyrA
DNA topoisomerase (ATP-hydrolyzing) subunit A, GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in [...]
     
 0.752
Your Current Organism:
Staphylococcus haemolyticus
NCBI taxonomy Id: 1283
Other names: ATCC 29970, CCM 2737, CCUG 7323, CIP 81.56, DSM 20263, JCM 2416, LMG 13349, LMG:13349, NCTC 11042, NRRL B-14755, S. haemolyticus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.