Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
merP_2MerTP family mercury (Hg2+) permease, binding protein MerP. (69 aa)    
Predicted Functional Partners:
copA_3
P-ATPase superfamily P-type ATPase copper (Cu2+)transporter.
  
 
 0.902
zupT
Zinc transporter ZupT.
     
 0.846
znuC
Zinc ABC transporter.
     
 0.802
csoR_2
Copper-sensing transcriptional repressor CsoR.
  
  
 0.784
copA_2
P-ATPase superfamily P-type ATPase copper (Cu2+)transporter.
  
 
 0.774
copA_1
P-ATPase superfamily P-type ATPase copper (Cu2+)transporter.
  
 
 0.707
topB
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
      
 0.693
AKC77253.1
Hypothetical protein.
   
 
 0.656
AKC77233.1
Transcriptional repressor.
  
  
 0.655
cadX_1
Cadmium efflux system accessory protein.
     
 0.599
Your Current Organism:
Staphylococcus haemolyticus
NCBI taxonomy Id: 1283
Other names: ATCC 29970, CCM 2737, CCUG 7323, CIP 81.56, DSM 20263, JCM 2416, LMG 13349, LMG:13349, NCTC 11042, NRRL B-14755, S. haemolyticus
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