STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKC77283.1Bifunctional cystathionine gamma-lyase/gamma-synthase. (391 aa)    
Predicted Functional Partners:
metH
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
 
 0.999
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
 
 
 0.997
AKC77282.1
Bifunctional cystathionine gamma-lyase/gamma-synthase.
 
  
 
0.988
cysM
Cystathionine beta-synthase, CysM.
 0.966
cysK
Cysteine synthase (o-acetylserine sulfhydrylase), CysK; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.959
AKC76925.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.940
metB_1
Bifunctional cystathionine gamma-lyase/gamma-synthase.
 
 
0.934
AKC75032.1
Aromatic amino acid transferase.
 
 
 0.933
luxS
Autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.922
metB_2
Bifunctional cystathionine gamma-lyase/gamma-synthase.
  
  
 
0.908
Your Current Organism:
Staphylococcus haemolyticus
NCBI taxonomy Id: 1283
Other names: ATCC 29970, CCM 2737, CCUG 7323, CIP 81.56, DSM 20263, JCM 2416, LMG 13349, LMG:13349, NCTC 11042, NRRL B-14755, S. haemolyticus
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