S40285_10714 protein (Stachybotrys chlorohalonata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

S40285_10714

Uncharacterized protein. (115 aa)

Predicted Functional Partners:

S40285_08989

0.937

S40285_00553

0.839

S40285_07853

0.587

S40285_03210

0.552

S40285_01223

0.552

S40285_01237

0.494

S40285_08079

0.487

S40285_00745

0.471

S40285_06456

0.467

S40285_02185

0.459

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00553	S40285_08989	A0A084R2L4	A0A084QEW8	Uncharacterized protein.	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.	0.839
S40285_00553	S40285_10714	A0A084R2L4	A0A084Q7X9	Uncharacterized protein.	Uncharacterized protein.	0.839
S40285_00745	S40285_01223	A0A084QR96	A0A084QY13	Uncharacterized protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.559
S40285_00745	S40285_02185	A0A084QR96	A0A084QB40	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.530
S40285_00745	S40285_03210	A0A084QR96	A0A084QNI0	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.559
S40285_00745	S40285_06456	A0A084QR96	A0A084QB88	Uncharacterized protein.	GRIP domain-containing protein.	0.594
S40285_00745	S40285_08079	A0A084QR96	A0A084Q925	Uncharacterized protein.	Guanylate kinase-like domain-containing protein.	0.695
S40285_00745	S40285_08989	A0A084QR96	A0A084QEW8	Uncharacterized protein.	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.	0.471
S40285_00745	S40285_10714	A0A084QR96	A0A084Q7X9	Uncharacterized protein.	Uncharacterized protein.	0.471
S40285_01223	S40285_00745	A0A084QY13	A0A084QR96	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Uncharacterized protein.	0.559
S40285_01223	S40285_02185	A0A084QY13	A0A084QB40	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Pyruvate carboxyltransferase domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.494
S40285_01223	S40285_03210	A0A084QY13	A0A084QNI0	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Serine/threonine-protein phosphatase.	0.861
S40285_01223	S40285_06456	A0A084QY13	A0A084QB88	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	GRIP domain-containing protein.	0.431
S40285_01223	S40285_08079	A0A084QY13	A0A084Q925	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Guanylate kinase-like domain-containing protein.	0.541
S40285_01223	S40285_08989	A0A084QY13	A0A084QEW8	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.	0.552
S40285_01223	S40285_10714	A0A084QY13	A0A084Q7X9	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Uncharacterized protein.	0.552
S40285_01237	S40285_02185	A0A084QQW7	A0A084QB40	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.660
S40285_01237	S40285_07853	A0A084QQW7	A0A084QFC1	Uncharacterized protein.	Uncharacterized protein.	0.713
S40285_01237	S40285_08989	A0A084QQW7	A0A084QEW8	Uncharacterized protein.	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family.	0.494
S40285_01237	S40285_10714	A0A084QQW7	A0A084Q7X9	Uncharacterized protein.	Uncharacterized protein.	0.494

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.786

expected number of edges:

14

PPI enrichment p-value:

0.000249

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034968

Histone lysine methylation

5 of 47

2.41

3.74

4.71e-08

GO:0051568

Histone H3-K4 methylation

4 of 20

2.68

3.6

1.82e-07

GO:0010228

Vegetative to reproductive phase transition of meristem

4 of 74

2.11

2.48

9.69e-06

GO:0080182

Histone H3-K4 trimethylation

2 of 7

2.84

1.61

0.0012

GO:0048608

Reproductive structure development

6 of 677

1.33

1.45

4.66e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042393

Histone binding

4 of 132

1.86

1.63

0.00044

GO:0003682

Chromatin binding

4 of 181

1.72

1.46

0.00076

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0048188

Set1C/COMPASS complex

3 of 14

2.71

2.46

2.97e-05

GO:0005654

Nucleoplasm

4 of 414

1.37

1.03

0.0031

GO:0140513

Nuclear protein-containing complex

5 of 869

1.14

0.88

0.0031

GO:1990234

Transferase complex

4 of 609

1.2

0.77

0.0113

GO:0005634

Nucleus

8 of 5765

0.52

0.32

0.0457

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:16168

Structural constituent of chromatin, and PKMTs methylate histone lysines

7 of 80

2.32

5.36

5.05e-12

CL:16178

Nucleosome core, and PKMTs methylate histone lysines

4 of 45

2.33

2.97

1.61e-06

CL:16291

Mixed, incl. Set1C/COMPASS complex, and Negative regulation of protein acetylation

3 of 12

2.78

2.74

8.84e-06

CL:16182

Nucleosome core, and HMGB9-like, ARID/BRIGHT DNA binding domain

3 of 23

2.5

2.34

4.10e-05

CL:16293

Set1C/COMPASS complex, and MORF/ORRM1/DAG-like

2 of 5

2.98

1.69

0.00087

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-74160

Gene expression (Transcription)

6 of 1140

1.1

0.88

0.0021

MAP-201681

TCF dependent signaling in response to WNT

2 of 29

2.22

0.83

0.0297

MAP-3214841

PKMTs methylate histone lysines

2 of 45

2.03

0.81

0.0297

MAP-3371497

HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand

2 of 66

1.86

0.73

0.0413

MAP-195721

Signaling by WNT

2 of 78

1.79

0.7

0.0444

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0048188

Set1C/COMPASS complex

4 of 15

2.81

3.82

7.98e-08

GOCC:0005654

Nucleoplasm

6 of 415

1.54

2.12

1.24e-06

GOCC:0035060

Brahma complex

2 of 3

3.2

2.07

0.00018

GOCC:0031981

Nuclear lumen

8 of 800

1.38

2.01

7.98e-08

GOCC:1902494

Catalytic complex

7 of 1276

1.12

1.2

2.46e-05

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037353

Histone methyltransferase complex subunit ASH2

2 of 2

3.38

1.25

0.0056

IPR029295

Snf2, ATP coupling domain

2 of 3

3.2

1.25

0.0056

IPR043136

B30.2/SPRY domain superfamily

2 of 6

2.9

1.21

0.0065

IPR014012

Helicase/SANT-associated domain

2 of 6

2.9

1.21

0.0065

IPR003877

SPRY domain

2 of 5

2.98

1.21

0.0065

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01314

Snf2-ATP coupling, chromatin remodelling complex

2 of 3

3.2

1.73

0.00077

SM00449

Domain in SPla and the RYanodine Receptor.

2 of 4

3.08

1.72

0.00077

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2024

Credits

Access

Info

About