S40285_07961 protein (Stachybotrys chlorohalonata)

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S40285_07961

Peptidase_S9 domain-containing protein. (270 aa)

Predicted Functional Partners:

S40285_01691

0.550

S40285_01541

0.536

S40285_06130

0.536

S40285_09545

0.536

S40285_01232

0.514

S40285_01358

0.498

S40285_01234

0.498

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_01232	S40285_07961	A0A084QXV7	A0A084Q9A8	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Peptidase_S9 domain-containing protein.	0.514
S40285_01234	S40285_01358	A0A084QY20	A0A084QLD1	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	FSH1 domain-containing protein.	0.841
S40285_01234	S40285_07961	A0A084QY20	A0A084Q9A8	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Peptidase_S9 domain-containing protein.	0.498
S40285_01358	S40285_01234	A0A084QLD1	A0A084QY20	FSH1 domain-containing protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.841
S40285_01358	S40285_07961	A0A084QLD1	A0A084Q9A8	FSH1 domain-containing protein.	Peptidase_S9 domain-containing protein.	0.498
S40285_01541	S40285_01691	A0A084QMQ7	A0A084QDZ8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	2Fe-2S ferredoxin-type domain-containing protein.	0.782
S40285_01541	S40285_06130	A0A084QMQ7	A0A084QPB1	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.855
S40285_01541	S40285_07961	A0A084QMQ7	A0A084Q9A8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Peptidase_S9 domain-containing protein.	0.536
S40285_01541	S40285_09545	A0A084QMQ7	A0A084QTF8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.853
S40285_01691	S40285_01541	A0A084QDZ8	A0A084QMQ7	2Fe-2S ferredoxin-type domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.782
S40285_01691	S40285_06130	A0A084QDZ8	A0A084QPB1	2Fe-2S ferredoxin-type domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.782
S40285_01691	S40285_07961	A0A084QDZ8	A0A084Q9A8	2Fe-2S ferredoxin-type domain-containing protein.	Peptidase_S9 domain-containing protein.	0.550
S40285_01691	S40285_09545	A0A084QDZ8	A0A084QTF8	2Fe-2S ferredoxin-type domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.782
S40285_06130	S40285_01541	A0A084QPB1	A0A084QMQ7	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.855
S40285_06130	S40285_01691	A0A084QPB1	A0A084QDZ8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	2Fe-2S ferredoxin-type domain-containing protein.	0.782
S40285_06130	S40285_07961	A0A084QPB1	A0A084Q9A8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Peptidase_S9 domain-containing protein.	0.536
S40285_06130	S40285_09545	A0A084QPB1	A0A084QTF8	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.855
S40285_07961	S40285_01232	A0A084Q9A8	A0A084QXV7	Peptidase_S9 domain-containing protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.514
S40285_07961	S40285_01234	A0A084Q9A8	A0A084QY20	Peptidase_S9 domain-containing protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.498
S40285_07961	S40285_01358	A0A084Q9A8	A0A084QLD1	Peptidase_S9 domain-containing protein.	FSH1 domain-containing protein.	0.498

page 1 of 2

Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009165

Nucleotide biosynthetic process

6 of 182

1.75

2.29

3.91e-06

GO:0009152

Purine ribonucleotide biosynthetic process

5 of 122

1.84

2.21

1.37e-05

GO:0009132

Nucleoside diphosphate metabolic process

4 of 69

1.99

2.17

3.33e-05

GO:0090407

Organophosphate biosynthetic process

7 of 397

1.47

1.89

3.91e-06

GO:0009141

Nucleoside triphosphate metabolic process

4 of 119

1.75

1.72

0.00018

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016776

Phosphotransferase activity, phosphate group as acceptor

4 of 29

2.37

2.68

7.11e-06

GO:0019205

Nucleobase-containing compound kinase activity

4 of 40

2.23

2.51

1.17e-05

GO:0004550

Nucleoside diphosphate kinase activity

3 of 15

2.53

2.13

0.00011

GO:0004017

Adenylate kinase activity

2 of 10

2.53

1.02

0.0138

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:35194983

(2022) Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation.

7 of 37

2.5

6.06

5.93e-13

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9802

Purine metabolism, and Interconversion of nucleotide di- and triphosphates

8 of 90

2.18

5.5

2.87e-13

CL:9804

Purine metabolism

7 of 76

2.19

5.05

6.68e-12

CL:9865

Mixed, incl. Purine ribonucleoside monophosphate biosynthetic process, and Uridine-diphosphatase activity

4 of 26

2.42

3.14

8.94e-07

CL:9919

Adenylate kinase activity, and dATP metabolic process

3 of 10

2.71

2.58

1.74e-05

CL:9923

Adenylate kinase activity

2 of 5

2.83

1.46

0.0022

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

acs00230

Purine metabolism

8 of 117

2.06

5.32

8.91e-14

acs00240

Pyrimidine metabolism

3 of 52

1.99

1.82

0.00022

acs00730

Thiamine metabolism

2 of 13

2.42

1.54

0.0014

acs01100

Metabolic pathways

8 of 1303

1.02

1.1

6.73e-06

acs00983

Drug metabolism - other enzymes

2 of 51

1.82

0.94

0.0143

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

4 of 34

2.3

2.63

7.91e-06

MAP-15869

Metabolism of nucleotides

5 of 122

1.84

2.29

7.91e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR034907

Nucleoside diphosphate kinase-like domain

3 of 5

3.01

2.37

4.96e-05

IPR036850

Nucleoside diphosphate kinase-like domain superfamily

3 of 6

2.93

2.36

4.96e-05

IPR001564

Nucleoside diphosphate kinase

2 of 4

2.93

1.13

0.0092

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00562

These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.

3 of 6

2.93

2.75

9.68e-06

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