S40285_04846 protein (Stachybotrys chlorohalonata)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

S40285_04846

Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (516 aa)

Predicted Functional Partners:

S40285_06726

0.707

S40285_06697

0.683

S40285_01575

0.633

S40285_06341

0.612

S40285_07716

0.612

S40285_06509

0.612

S40285_04646

0.612

S40285_02623

0.612

S40285_00052

0.612

S40285_01744

0.612

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00052	S40285_01744	A0A084QYY6	A0A084R2B7	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
S40285_00052	S40285_04846	A0A084QYY6	A0A084QA89	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.612
S40285_01575	S40285_04846	A0A084QW97	A0A084QA89	ULP_PROTEASE domain-containing protein.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.633
S40285_01744	S40285_00052	A0A084R2B7	A0A084QYY6	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
S40285_01744	S40285_04846	A0A084R2B7	A0A084QA89	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.612
S40285_02623	S40285_04846	A0A084QXJ7	A0A084QA89	Uncharacterized protein.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.612
S40285_04646	S40285_04846	A0A084QPG0	A0A084QA89	Uncharacterized protein; Belongs to the FGGY kinase family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.612
S40285_04646	S40285_06341	A0A084QPG0	A0A084QAT5	Uncharacterized protein; Belongs to the FGGY kinase family.	Uncharacterized protein; Belongs to the FGGY kinase family.	0.883
S40285_04846	S40285_00052	A0A084QA89	A0A084QYY6	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.612
S40285_04846	S40285_01575	A0A084QA89	A0A084QW97	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	ULP_PROTEASE domain-containing protein.	0.633
S40285_04846	S40285_01744	A0A084QA89	A0A084R2B7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.612
S40285_04846	S40285_02623	A0A084QA89	A0A084QXJ7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.612
S40285_04846	S40285_04646	A0A084QA89	A0A084QPG0	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the FGGY kinase family.	0.612
S40285_04846	S40285_06341	A0A084QA89	A0A084QAT5	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the FGGY kinase family.	0.612
S40285_04846	S40285_06509	A0A084QA89	A0A084QMG0	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	ATPase_AAA_core domain-containing protein.	0.612
S40285_04846	S40285_06697	A0A084QA89	A0A084QA37	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.683
S40285_04846	S40285_06726	A0A084QA89	A0A084QJE7	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	cAMP-dependent protein kinase regulatory subunit.	0.707
S40285_04846	S40285_07716	A0A084QA89	A0A084QE42	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.612
S40285_06341	S40285_04646	A0A084QAT5	A0A084QPG0	Uncharacterized protein; Belongs to the FGGY kinase family.	Uncharacterized protein; Belongs to the FGGY kinase family.	0.883
S40285_06341	S40285_04846	A0A084QAT5	A0A084QA89	Uncharacterized protein; Belongs to the FGGY kinase family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.612

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Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.881

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000096

Sulfur amino acid metabolic process

3 of 22

1.91

1.04

0.0097

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008705

Methionine synthase activity

2 of 2

2.77

1.09

0.0106

GO:0031419

Cobalamin binding

2 of 3

2.6

1.08

0.0106

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9085

Mixed, incl. Transsulfuration, and Hint domain superfamily

3 of 6

2.47

1.83

0.00040

CL:540

Homocysteine-binding domain, and Transsulfuration

2 of 5

2.37

0.88

0.0242

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00270

Cysteine and methionine metabolism

3 of 37

1.68

1.13

0.0045

map00450

Selenocompound metabolism

2 of 21

1.75

0.71

0.0421

map04122

Sulfur relay system

2 of 26

1.66

0.7

0.0421

map00670

One carbon pool by folate

2 of 29

1.61

0.69

0.0421

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02574

Homocysteine S-methyltransferase

2 of 3

2.6

0.95

0.0191

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036873

Rhodanese-like domain superfamily

4 of 14

2.23

2.37

2.41e-05

IPR001763

Rhodanese-like domain

4 of 15

2.2

2.35

2.41e-05

IPR036589

Homocysteine-binding domain superfamily

2 of 3

2.6

0.99

0.0157

IPR003726

Homocysteine-binding domain

2 of 3

2.6

0.99

0.0157

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00450

Rhodanese Homology Domain

4 of 14

2.23

2.87

1.92e-06

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