S40285_05572 protein (Stachybotrys chlorohalonata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

Experiments

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[Homology]

Score

S40285_05572

Uncharacterized protein. (113 aa)

Predicted Functional Partners:

S40285_05043

0.843

S40285_07235

0.718

S40285_06936

0.716

S40285_06143

0.701

S40285_01305

0.699

S40285_07310

0.688

S40285_00147

0.686

S40285_10649

0.685

S40285_01540

0.668

S40285_03989

0.655

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00147	S40285_05572	A0A084QU31	A0A084QEY3	Protein kinase domain-containing protein.	Uncharacterized protein.	0.686
S40285_01305	S40285_01540	A0A084QQV2	A0A084QMM0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.999
S40285_01305	S40285_05043	A0A084QQV2	A0A084QFK1	Uncharacterized protein.	Uncharacterized protein.	0.999
S40285_01305	S40285_05572	A0A084QQV2	A0A084QEY3	Uncharacterized protein.	Uncharacterized protein.	0.699
S40285_01305	S40285_06143	A0A084QQV2	A0A084QL33	Uncharacterized protein.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.999
S40285_01305	S40285_07310	A0A084QQV2	A0A084QRK1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.999
S40285_01540	S40285_01305	A0A084QMM0	A0A084QQV2	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
S40285_01540	S40285_05043	A0A084QMM0	A0A084QFK1	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
S40285_01540	S40285_05572	A0A084QMM0	A0A084QEY3	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.668
S40285_01540	S40285_06143	A0A084QMM0	A0A084QL33	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.999
S40285_01540	S40285_07310	A0A084QMM0	A0A084QRK1	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.999
S40285_03989	S40285_05572	A0A084QC92	A0A084QEY3	Uncharacterized protein.	Uncharacterized protein.	0.655
S40285_03989	S40285_06936	A0A084QC92	A0A084QBB5	Uncharacterized protein.	B30.2/SPRY domain-containing protein.	0.913
S40285_03989	S40285_07235	A0A084QC92	A0A084QGE3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.931
S40285_03989	S40285_10649	A0A084QC92	A0A084QW07	Uncharacterized protein.	Amidase domain-containing protein.	0.524
S40285_05043	S40285_01305	A0A084QFK1	A0A084QQV2	Uncharacterized protein.	Uncharacterized protein.	0.999
S40285_05043	S40285_01540	A0A084QFK1	A0A084QMM0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.999
S40285_05043	S40285_05572	A0A084QFK1	A0A084QEY3	Uncharacterized protein.	Uncharacterized protein.	0.843
S40285_05043	S40285_06143	A0A084QFK1	A0A084QL33	Uncharacterized protein.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.999
S40285_05043	S40285_07310	A0A084QFK1	A0A084QRK1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.999

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Network Stats

number of nodes:

7

number of edges:

6

average node degree:

1.71

avg. local clustering coefficient:

0.857

expected number of edges:

6

PPI enrichment p-value:

0.555

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016491

Oxidoreductase activity

6 of 913

1.11

1.0

0.00087

GO:0046872

Metal ion binding

6 of 1345

0.94

0.72

0.0043

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 756

1.12

0.82

0.0076

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8839

2OG-Fe(II) oxygenase superfamily

7 of 18

2.88

9.73

4.39e-17

CL:8842

2OG-Fe(II) oxygenase superfamily

6 of 11

3.03

8.84

3.90e-15

CL:8844

2OG-Fe(II) oxygenase superfamily

3 of 6

2.99

3.61

1.93e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01110

Biosynthesis of secondary metabolites

6 of 669

1.25

1.47

1.31e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-549127

Organic cation transport

6 of 25

2.67

7.19

5.05e-13

MAP-8981373

Intestinal hexose absorption

6 of 26

2.66

7.16

5.05e-13

MAP-8963676

Intestinal absorption

6 of 26

2.66

7.16

5.05e-13

MAP-549132

Organic cation/anion/zwitterion transport

6 of 26

2.66

7.16

5.05e-13

MAP-8963743

Digestion and absorption

6 of 37

2.5

6.76

8.36e-13

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000407

Phagophore assembly site

6 of 32

2.57

6.7

1.94e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0408

Iron

6 of 135

1.94

4.01

1.69e-09

KW-0560

Oxidoreductase

6 of 253

1.67

2.9

3.39e-08

KW-0479

Metal-binding

6 of 717

1.22

1.43

1.08e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03171

2OG-Fe(II) oxygenase superfamily

7 of 24

2.76

9.19

1.54e-16

PF14226

Non-haem dioxygenase in morphine synthesis N-terminal

7 of 25

2.74

9.15

1.54e-16

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR044861

Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain

7 of 24

2.76

8.96

4.26e-16

IPR026992

Non-haem dioxygenase N-terminal domain

7 of 25

2.74

8.92

4.26e-16

IPR027443

Isopenicillin N synthase-like superfamily

7 of 26

2.72

8.88

4.26e-16

IPR005123

Oxoglutarate/iron-dependent dioxygenase

7 of 38

2.56

8.16

1.84e-15

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