S40285_01010 protein (Stachybotrys chlorohalonata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

S40285_01010

Uncharacterized protein. (439 aa)

Predicted Functional Partners:

S40285_01680

0.976

S40285_06809

0.976

S40285_00151

0.942

S40285_08302

0.864

S40285_03768

0.754

S40285_02229

0.726

S40285_07179

0.696

S40285_03751

0.623

S40285_03770

0.615

S40285_04294

0.602

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00151	S40285_01010	A0A084QTW4	A0A084QK93	zf-Tim10_DDP domain-containing protein.	Uncharacterized protein.	0.942
S40285_00151	S40285_01680	A0A084QTW4	A0A084QDV6	zf-Tim10_DDP domain-containing protein.	Uncharacterized protein.	0.988
S40285_00151	S40285_02229	A0A084QTW4	A0A084QG24	zf-Tim10_DDP domain-containing protein.	Uncharacterized protein.	0.670
S40285_00151	S40285_03751	A0A084QTW4	A0A084QIZ9	zf-Tim10_DDP domain-containing protein.	Tim44 domain-containing protein.	0.505
S40285_00151	S40285_03768	A0A084QTW4	A0A084QIX4	zf-Tim10_DDP domain-containing protein.	DAGKc domain-containing protein.	0.473
S40285_00151	S40285_03770	A0A084QTW4	A0A084QIY2	zf-Tim10_DDP domain-containing protein.	BTB domain-containing protein.	0.473
S40285_00151	S40285_06809	A0A084QTW4	A0A084QIV2	zf-Tim10_DDP domain-containing protein.	zf-Tim10_DDP domain-containing protein.	0.999
S40285_00151	S40285_07179	A0A084QTW4	A0A084QPW2	zf-Tim10_DDP domain-containing protein.	Uncharacterized protein.	0.894
S40285_00151	S40285_08302	A0A084QTW4	A0A084Q8T1	zf-Tim10_DDP domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit.	0.886
S40285_01010	S40285_00151	A0A084QK93	A0A084QTW4	Uncharacterized protein.	zf-Tim10_DDP domain-containing protein.	0.942
S40285_01010	S40285_01680	A0A084QK93	A0A084QDV6	Uncharacterized protein.	Uncharacterized protein.	0.976
S40285_01010	S40285_02229	A0A084QK93	A0A084QG24	Uncharacterized protein.	Uncharacterized protein.	0.726
S40285_01010	S40285_03751	A0A084QK93	A0A084QIZ9	Uncharacterized protein.	Tim44 domain-containing protein.	0.623
S40285_01010	S40285_03768	A0A084QK93	A0A084QIX4	Uncharacterized protein.	DAGKc domain-containing protein.	0.754
S40285_01010	S40285_03770	A0A084QK93	A0A084QIY2	Uncharacterized protein.	BTB domain-containing protein.	0.615
S40285_01010	S40285_04294	A0A084QK93	A0A084QQ82	Uncharacterized protein.	HMG box domain-containing protein.	0.602
S40285_01010	S40285_06809	A0A084QK93	A0A084QIV2	Uncharacterized protein.	zf-Tim10_DDP domain-containing protein.	0.976
S40285_01010	S40285_07179	A0A084QK93	A0A084QPW2	Uncharacterized protein.	Uncharacterized protein.	0.696
S40285_01010	S40285_08302	A0A084QK93	A0A084Q8T1	Uncharacterized protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit.	0.864
S40285_01680	S40285_00151	A0A084QDV6	A0A084QTW4	Uncharacterized protein.	zf-Tim10_DDP domain-containing protein.	0.988

page 1 of 4

Network Stats

number of nodes:

6

number of edges:

7

average node degree:

2.33

avg. local clustering coefficient:

0.867

expected number of edges:

5

PPI enrichment p-value:

0.281

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006631

Fatty acid metabolic process

7 of 101

1.71

2.76

6.02e-08

GO:0006635

Fatty acid beta-oxidation

4 of 29

2.01

2.21

2.97e-05

GO:0046395

Carboxylic acid catabolic process

5 of 111

1.53

1.66

6.47e-05

GO:0140647

P450-containing electron transport chain

2 of 2

2.87

1.53

0.0017

GO:0010124

Phenylacetate catabolic process

2 of 2

2.87

1.53

0.0017

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

2 of 2

2.87

1.02

0.0143

GO:0003988

acetyl-CoA C-acyltransferase activity

2 of 5

2.47

1.01

0.0143

GO:0016747

Acyltransferase activity, transferring groups other than amino-acyl groups

4 of 123

1.38

0.82

0.0143

GO:0016491

Oxidoreductase activity

6 of 689

0.81

0.49

0.0279

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005777

Peroxisome

3 of 67

1.52

0.7

0.0379

GO:0005739

Mitochondrion

7 of 822

0.8

0.51

0.0195

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:8342

Fatty acid beta-oxidation, and Acyl-CoA dehydrogenase, conserved site

4 of 17

2.24

2.65

6.17e-06

CL:8692

Mixed, incl. Lipoate metabolic process, and Ergot alkaloid metabolic process

3 of 5

2.65

2.61

1.44e-05

CL:8329

Mixed, incl. Fatty acid catabolic process, and Branched-chain amino acid catabolism

5 of 47

1.9

2.41

5.42e-06

CL:8316

Mixed, incl. Fatty acid degradation, and NAD(P)-binding domain superfamily

6 of 135

1.52

1.92

6.17e-06

CL:8360

Beta-oxidation of very long chain fatty acids, and Beta oxidation of butanoyl-CoA to acetyl-CoA

2 of 8

2.27

1.18

0.0064

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01212

Fatty acid metabolism

4 of 96

1.49

1.37

0.00049

map00061

Fatty acid biosynthesis

2 of 19

1.89

0.92

0.0171

map00592

alpha-Linolenic acid metabolism

2 of 24

1.79

0.9

0.0171

map00190

Oxidative phosphorylation

3 of 116

1.29

0.76

0.0171

map00071

Fatty acid degradation

2 of 45

1.52

0.7

0.0371

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-390247

Beta-oxidation of very long chain fatty acids

3 of 7

2.5

2.18

8.67e-05

MAP-2046106

Alpha-linolenic acid (ALA) metabolism

3 of 13

2.24

1.95

0.00018

MAP-2046104

Alpha-linolenic (omega3) and linoleic (omega6) acid metabolism

3 of 13

2.24

1.95

0.00018

MAP-8978868

Fatty acid metabolism

6 of 138

1.51

1.85

1.03e-05

MAP-77289

Mitochondrial Fatty Acid Beta-Oxidation

3 of 25

1.95

1.56

0.00075

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02803

Thiolase, C-terminal domain

2 of 4

2.57

1.02

0.0141

PF00108

Thiolase, N-terminal domain

2 of 3

2.7

1.02

0.0141

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016039

Thiolase-like

3 of 19

2.07

1.13

0.0070

IPR020613

Thiolase, conserved site

2 of 3

2.7

0.93

0.0210

IPR020617

Thiolase, C-terminal

2 of 4

2.57

0.92

0.0210

IPR020616

Thiolase, N-terminal

2 of 4

2.57

0.92

0.0210

IPR002155

Thiolase

2 of 4

2.57

0.92

0.0210

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